{"version":"1.0","provider_name":"acupuncture, fertility massage, clapham","provider_url":"https:\/\/silenebricet.com\/fr","author_name":"Silene Bricet","author_url":"https:\/\/silenebricet.com\/fr\/author\/silene\/","title":"Miscarriages: what tests need to be done? - acupuncture, fertility massage, clapham","type":"rich","width":600,"height":338,"html":"<blockquote class=\"wp-embedded-content\" data-secret=\"Tp7hojTIzg\"><a href=\"https:\/\/silenebricet.com\/fr\/miscarriages-what-tests-need-to-be-done\/\">Miscarriages: what tests need to be done?<\/a><\/blockquote><iframe sandbox=\"allow-scripts\" security=\"restricted\" src=\"https:\/\/silenebricet.com\/fr\/miscarriages-what-tests-need-to-be-done\/embed\/#?secret=Tp7hojTIzg\" width=\"600\" height=\"338\" title=\"\u00ab\u00a0Miscarriages: what tests need to be done?\u00a0\u00bb &#8212; acupuncture, fertility massage, clapham\" data-secret=\"Tp7hojTIzg\" frameborder=\"0\" marginwidth=\"0\" marginheight=\"0\" scrolling=\"no\" class=\"wp-embedded-content\"><\/iframe><script>\n\/*! This file is auto-generated *\/\n!function(d,l){\"use strict\";l.querySelector&&d.addEventListener&&\"undefined\"!=typeof URL&&(d.wp=d.wp||{},d.wp.receiveEmbedMessage||(d.wp.receiveEmbedMessage=function(e){var t=e.data;if((t||t.secret||t.message||t.value)&&!\/[^a-zA-Z0-9]\/.test(t.secret)){for(var s,r,n,a=l.querySelectorAll('iframe[data-secret=\"'+t.secret+'\"]'),o=l.querySelectorAll('blockquote[data-secret=\"'+t.secret+'\"]'),c=new RegExp(\"^https?:$\",\"i\"),i=0;i<o.length;i++)o[i].style.display=\"none\";for(i=0;i<a.length;i++)s=a[i],e.source===s.contentWindow&&(s.removeAttribute(\"style\"),\"height\"===t.message?(1e3<(r=parseInt(t.value,10))?r=1e3:~~r<200&&(r=200),s.height=r):\"link\"===t.message&&(r=new URL(s.getAttribute(\"src\")),n=new URL(t.value),c.test(n.protocol))&&n.host===r.host&&l.activeElement===s&&(d.top.location.href=t.value))}},d.addEventListener(\"message\",d.wp.receiveEmbedMessage,!1),l.addEventListener(\"DOMContentLoaded\",function(){for(var e,t,s=l.querySelectorAll(\"iframe.wp-embedded-content\"),r=0;r<s.length;r++)(t=(e=s[r]).getAttribute(\"data-secret\"))||(t=Math.random().toString(36).substring(2,12),e.src+=\"#?secret=\"+t,e.setAttribute(\"data-secret\",t)),e.contentWindow.postMessage({message:\"ready\",secret:t},\"*\")},!1)))}(window,document);\n\/\/# sourceURL=https:\/\/silenebricet.com\/wp-includes\/js\/wp-embed.min.js\n<\/script>","thumbnail_url":"https:\/\/silenebricet.com\/wp-content\/uploads\/2024\/01\/pexels-cottonbro-studio-6542718-1.jpg","thumbnail_width":1000,"thumbnail_height":1210,"description":"If you\u2019ve experienced one or two miscarriages, it can feel frustrating and heartbreaking to hear doctors say, \u201cWe only start investigations after the third.\u201d But there\u2019s a reason behind this, and understanding it can help you feel a little more informed and empowered.  Why Do Miscarriages Happen?  The most common reason for early miscarriage is a problem with the baby\u2019s chromosomes. These are the bits of DNA that carry genetic information. When an egg and sperm meet, they\u2019re supposed to bring the right amount of chromosomes. But sometimes, especially as we get older, this process goes wrong.  Here\u2019s the tricky part: as women, we\u2019re born with all our eggs already inside us. Those eggs have been sitting there since before we were born! As we age, especially in our late 30s and 40s, those eggs are more likely to have trouble splitting their chromosomes correctly when it\u2019s time to ovulate. This can lead to embryos with the wrong number of chromosomes\u2014and unfortunately, most of those won\u2019t survive.  After 3 Miscarriages: What Tests Can Be Done?  Once you\u2019ve had 3 miscarriages, doctors usually offer more in-depth testing to see if something else might be going on. Here\u2019s what they might look at:  Blood clotting issues - Thrombotic Risk ProfileConditions like antiphospholipid syndrome can cause tiny blood clots in the placenta and stop an embryo from growing. Simple blood tests can check for this. It is called Thrombotic Risk Profile. Baby aspirin and heparin (a blood thinner) are sometimes used for clotting issues.   Full Blood Count (FBC)  Coagulation Profile 1  Antithrombin III  Factor V Leiden \u2013 G1691A Variant  Factor II Prothrombin \u2013 G20210A Variant  MTHFR \u2013 common C677T + A1298C variants  Lupus Anticoagulant  Protein C  Free Protein S Ag  Cardiolipin Antibodies (IgG+IgM)   Sperm DNA fragmentationEven if a sperm test looks \u201cnormal,\u201d the DNA inside might be damaged. High levels of DNA fragmentation have been linked to miscarriage. A special sperm test can check this. An andrologist would run this test.&nbsp;  Varicocele in menThis is when veins in the testicles are swollen. It can lead to higher sperm DNA damage. It\u2019s treatable if found.&nbsp;  Thyroid problemsAn underactive thyroid (even slightly) can increase miscarriage risk. Ideally, TSH (thyroid-stimulating hormone) should be close to 1 and definitely under 2.5. If your TSH is too high, you need to see an endocrinologist.  MTHFR gene mutationThis gene affects how your body uses folate (vitamin B9), which is crucial for cell division and healthy embryo development. If you have a mutation, your body might not process folic acid properly. The solution? Take the active form of folate (called methylfolate), so your body doesn\u2019t have to do the work. A nutritionist specialised in fertility would help you take the right supplement.&nbsp;  Chronic endometritisThis is low-level inflammation of the womb lining. It\u2019s hard to detect, but can sometimes be treated with antibiotics. A sonographer specialised in women's health would help you detect it.  Immune issuesSometimes, your immune system might react too strongly to a developing embryo. The embryo contains DNA from the father\u2014technically \u201cforeign\u201d\u2014and your body should normally adapt. But if this doesn\u2019t happen, implantation might fail. In some cases, immune-modulating treatments like steroids or IV infusions can help. Dr Thum from the Lister clinic is a specialist. Steroids, intralipids, or IV immunoglobulins are used for immune issues (though not always offered on the NHS).  Uterus shape and structureSome people are born with a uterus that\u2019s divided (like a wall down the middle), or shaped in a way that can make it hard for a baby to grow. Scans can check for this.  Testing the Embryos  In France, testing embryos (like with a biopsy) is only allowed if a parent carries a known genetic condition. But in the UK, if you\u2019re doing IVF privately, you can choose to test embryos for chromosome issues to reduce the risk of another miscarriage.  Karyotype testing (genetic tests for you and your partner)Karyotyping checks the chromosome set of both partners to rule out underlying genetic abnormalities that could be causing fertility issues.  Who else can help?  If you have had 3 miscarriages, ask your GP to refer you to Dr. Raj Rai at St Mary\u2019s Hospital in London. He is a leading experts on recurrent miscarriage.&nbsp;  Let me know if you have any questions,  All the best,  Silene&nbsp;"}